THE USE OF ENAMINES IN THE SYNTHESIS OF HETEROCYCLESMONTGOMERY JA; LASETER AG.1972; J. HETEROCYCL. CHEM.; U.S.A.; DA. 1972; VOL. 9; NO 5; PP. 1077-1079; BIBL. 7 REF.Serial Issue

Sugar-modified derivatives of cytostatic 7-(het)aryl-7-deazaadenosines: 2'-C-methylribonucleosides, 2'-deoxy-2'-fluoroarabinonucleosides, arabinonucleosides and 2'-deoxyribonucleosidesNAUS, Petr; PERLIKOVA, Pavla; BOURDERIOUX, Aurelie et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 17, pp 5202-5214, issn 0968-0896, 13 p.Article

N⁴-Aryl-6-substitutedphenylmethyl-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamines as receptor tyrosine kinase inhibitorsGANGJEE, Aleem; KURUP, Sonali; IHNAT, Michael A et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 2, pp 910-914, issn 0968-0896, 5 p.Article

Synthesis of deuterated-BCX-1777, a potent inhibitor of purine nucleoside phosphorylaseKEZAR, Hollis S; HUTCHISON, Tracy L; TYLER, Peter C et al.Journal of labelled compounds & radiopharmaceuticals. 2002, Vol 45, Num 1, pp 71-78, issn 0362-4803Article

Design and synthesis of pyrrolo[3,2-d]pyrimidine HER2/EGFR dual inhibitors: Improvement of the physicochemical and pharmacokinetic profiles for potent in vivo anti-tumor efficacyKAWAKITA, Youichi; MIWA, Kazuhiro; TANAKA, Toshimasa et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 20, pp 6171-6180, issn 0968-0896, 10 p.Article

Practical one-pot protocol for the syntheses of 2-chloro-pyrrolo[3,2-d]pyrimidinesLIWEN ZHAO; KEMEI TAO; HAITIAN LI et al.Tetrahedron (Oxford. Print). 2011, Vol 67, Num 15, issn 0040-4020, 2705, 2803-2806 [5 p.]Article

Synthesis of analogs of forodesine HCl, a human purine nucleoside phosphorylase inhibitor―Part IKAMATH, Vivekanand P; JIE XUE; JUAREZ-BRAMBILA, Jesus J et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 10, pp 2624-2626, issn 0960-894X, 3 p.Article

Synthesis of hybrid analogues of caffeine and eudistomin D and its affinity for adenosine receptorsISHIYAMA, Haruaki; NAKAJIMA, Hikaru; NAKATA, Hiroyasu et al.Bioorganic & medicinal chemistry. 2009, Vol 17, Num 13, pp 4280-4284, issn 0968-0896, 5 p.Article

Identification and synthesis of substituted pyrrolo[2,3-d]pyrimidines as novel firefly luciferase inhibitorsYANG LIU; JIANPING FANG; HAIYAN CAI et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 18, pp 5473-5482, issn 0968-0896, 10 p.Article

Design, Synthesis, and Biological Evaluation of Classical and Nonclassical 2-Amino-4-oxo-5-substituted-6-methylpyrrolo[3,2-d]pyrimidines as Dual Thymidylate Synthase and Dihydrofolate Reductase InhibitorsGANGJEE, Aleem; WEI LI; JIE YANG et al.Journal of medicinal chemistry (Print). 2008, Vol 51, Num 1, pp 68-76, issn 0022-2623, 9 p.Article

Exploring structure-activity relationships of transition state analogues of human purine nucleoside phosphorylaseEVANS, Gary B; FURNEAUX, Richard H; LEWANDOWICZ, Andrzej et al.Journal of medicinal chemistry (Print). 2003, Vol 46, Num 15, pp 3412-3423, issn 0022-2623, 12 p.Article

Design, synthesis and dopamine D4 receptor binding activities of new N-heteroaromatic 5/6-ring Mannich basesLINZ, Sabine; MÜLLER, Jörg; HÜBNER, Harald et al.Bioorganic & medicinal chemistry. 2009, Vol 17, Num 13, pp 4448-4458, issn 0968-0896, 11 p.Article

Facile Reductive Amination of Aldehydes with Electron-Deficient Anilines by Acyloxyborohydrides in TFA : Application to a Diazaindoline Scale-UpBOROS, Eric E; THOMPSON, James B; KATAMREDDY, Subba R et al.Journal of organic chemistry. 2009, Vol 74, Num 9, pp 3587-3590, issn 0022-3263, 4 p.Article

Azetidine Based Transition State Analogue Inhibitors of N-Ribosyl Hydrolases and PhosphorylasesEVANS, Gary B; FURNEAUX, Richard H; GREATREX, Ben et al.Journal of medicinal chemistry (Print). 2008, Vol 51, Num 4, pp 948-956, issn 0022-2623, 9 p.Article

Current Developments in the Synthesis and Biological Activity of Aza-C-Nucleosides : Immucillins and Related CompoundsMERINO, Pedro; TEJERO, Tomas; DELSO, Ignacio et al.Current medicinal chemistry. 2008, Vol 15, Num 10, pp 954-967, issn 0929-8673, 14 p.Article

Simplified analogues of immucillin-G retain potent human purine nucleoside phosphorylase inhibitory activitySEMERARO, Teresa; LOSSANI, Andrea; BOTTA, Maurizio et al.Journal of medicinal chemistry (Print). 2006, Vol 49, Num 20, pp 6037-6045, issn 0022-2623, 9 p.Article

Targeting the polyamine pathway with transition-state analogue inhibitors of 5'-methylthioadenosine phosphorylaseEVANS, Gary B; FURNEAUX, Richard H; SCHRAMM, Vern L et al.Journal of medicinal chemistry (Print). 2004, Vol 47, Num 12, pp 3275-3281, issn 0022-2623, 7 p.Article

Diversity-oriented synthesis of functionalized pyrrolo[3,2-d]pyrimidines with variation of the pyrimidine ring nitrogen substituentsMARCOTTE, Félix-Antoine; ROMBOUTS, Frederik J. R; LUBELL, William D et al.Journal of organic chemistry. 2003, Vol 68, Num 18, pp 6984-6987, issn 0022-3263, 4 p.Article

N⁴-(3-Bromophenyl)-7-(substituted benzyl) pyrrolo[2,3-d]pyrimidines as potent multiple receptor tyrosine kinase inhibitors: Design, synthesis, and in vivo evaluationGANGJEE, Aleem; ZAWARE, Nilesh; RAGHAVAN, Sudhir et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 7, pp 2444-2454, issn 0968-0896, 11 p.Article

Structure-based design of 2,6,7-trisubstituted-7H-pyrrolo[2,3-d]pyrimidines as Aurora kinases inhibitorsLE BRAZIDEC, Jean-Yves; PASIS, Angela; NGUYEN, Khanh et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 12, pp 4033-4037, issn 0960-894X, 5 p.Article

Synthesis of analogs of forodesine HCl, a human purine nucleoside phosphorylase inhibitor―Part IIKAMATH, Vivekanand P; JIE XUE; JUAREZ-BRAMBILA, Jesus J et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 10, pp 2627-2629, issn 0960-894X, 3 p.Article

Synthesis of a potent 5'-methylthioadenosine/S-adenosylhomocysteine (MTAN) inhibitorKAMATH, Vivekanand P; JAINWEN ZHANG; MORRIS, Philip E et al.Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 10, pp 2662-2665, issn 0960-894X, 4 p.Article

Synthesis of a potent transition-state inhibitor of 5'-deoxy-5'-methylthioadenosine phosphorylaseKAMATH, Vivekanand P; ANANTH, Sandya; BANTIA, Shanta et al.Journal of medicinal chemistry (Print). 2004, Vol 47, Num 6, pp 1322-1324, issn 0022-2623, 3 p.Article

Structure-activity relationships for a collection of structurally diverse inhibitors of purine nucleoside phosphorylaseANDRICOPULO, Adriano D; YUNES, Rosendo A.Chemical and pharmaceutical bulletin. 2001, Vol 49, Num 1, pp 10-17, issn 0009-2363Article

2-({6-[(3R)-3-amino-3-methylpiperidine-1-yl]-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-5H-pyrrolo[3,2-d]pyrimidine-5-yl}methyl)-4-fluorobenzonitrile (DSR-12727): A potent, orally active dipeptidyl peptidase IV inhibitor without mechanism-based inactivation of CYP3ANISHIO, Yukihiro; KIMURA, Hidenori; HASHIZUKA, Takahiko et al.Bioorganic & medicinal chemistry. 2011, Vol 19, Num 18, pp 5490-5499, issn 0968-0896, 10 p.Article